Indigenous Method and Safety of Mitomycin C in Refractory Corrosive Esophageal Strictures
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چکیده
منابع مشابه
Indigenous Method and Safety of Mitomycin C in Refractory Corrosive Esophageal Strictures
Caustic esophageal strictures still represent a challenge to endoscopist. Standard treatment is regular esophageal dilatation until the resolution of dysphagia. Caustic strictures require dilations more frequently for a positive clinical response [1]. Increasingly frequent dilation may become a selfdefeating cycle in refractory stricture as recurrent trauma to the mucosa, enhance scar formation...
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Introduction: Corrosive ingestion is the major cause of esophageal stricture in our country. Mitomycin–C, an anthracycline derived from Streptomyces caespitosus, has both antineoplastic and antiproliferative properties. Use of mitomycin–C have been well documented in various ophthalmologic procedures and laryngo-tracheal conditions where it has been shown that mitomycin–C inhibited fibroblast p...
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OBJECTIVES The aim of the present study was to evaluate the efficacy and short-term safety of topical mitomycin-C, an antifibrotic agent, in preventing the recurrence of anastomotic strictures after surgical repair of esophageal atresia (EA). METHODS We retrospectively reviewed the medical records of patients with recurrent anastomotic strictures after EA surgery who underwent at least 3 esop...
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bypass . . u r g r , j v r araarurruvss s v r r w * r c vsauyrsugcus rrr*a,rurcu wlth~n the I0;vearperiod of January 1978 to December 1987. Cervical complications accounted for 60% and the commonest was a leak at the colo-oesophageal anastomosis. There was one death due to undetected oesophago-tracheal fistula. The longest follow up was 10 years. ve oesophageal strictures
متن کاملEsophageal Strictures Refractory to Endoscopic Dilatation
Esophageal stricture is a common issue faced by clinicians who care for patients with foregut disorders. Generally, strictures can be effectively managed using endoscopic techniques such as dilation. Improved control of the primary pathology, in most cases gastroesophageal reflux disease (GERD), is also typically effective in limiting recurrence of a stricture after therapy. However, while many...
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ژورنال
عنوان ژورنال: Advanced Research in Gastroenterology & Hepatology
سال: 2017
ISSN: 2472-6400
DOI: 10.19080/argh.2017.04.555644